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LibrarYeast

Over the past two decades, genome-wide collections of mutants, or libraries, have revolutionized the fields of systems and cell biology by enabling systematic and high-throughput interrogation of gene and protein function. This has been especially prominent in the model yeast Saccharomyces cerevisiae. The unique genetic properties of yeast, combined with efficient genome engineering tools, have facilitated the creation of a large number of comprehensive collections of strains with targeted gene deletions, overexpressions, regulatable promoters, and protein tagging.

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These resources have enabled large-scale studies of cellular phenotypes, genetic and drug interactions, protein localization, protein-protein interactions, and much more. This tool provides a comprehensive overview of the available genomically altered and arrayed yeast libraries, highlighting their design, applications, and transformative impact on functional genomics.

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